Question: Down syndrome is caused by all except___________?

• 1. Trisomy of 21 chromosome
• 2. Mosaicism of 21 chromosome
• 3. Robersonian translocation of 21.21, 21.18
• 4. Deletion of 21

Question: NK cells are effective against viral infected cells only if the cell with infection___________?

• 1. Exprss MHC class I proteins
• 2. Unable to express MHC class I proteins
• 3. Express MHC class II proteins
• 4. Unable to express MHC class II proteins

Question: Tumour involving epiphysis of long bone is____________?

• 1. Osteogenic sarcoma
• 2. Osteoclastoma
• 3. Ewings sarcoma
• 4. Chondro sarcoma

Question: A haemophilia person has married to a normal woman Then his___________?

• 1. Daughter are carrier
• 2. Sons are infected
• 3. Daughter are infeted
• 4. All are normal

Question: A 13 year old boy presents with a large mixed lytic and blastic mass in the metaphyseal region of the lower end of femur. The most likely diagnosis is___________?

• 1. Ewing’s sarcoma
• 2. Osteosarcoma
• 3. Chondrosarcoma
• 4. Giant cell tumour

Question: Endotoxic shock is propagated____________?

• 1. Endothelial injury
• 2. Peripheral vasodilation
• 3. Increased vascular permeability
• 4. Cytokine action

Question: DiGeorge’s syndrome is due to___________?

• 1. Congenital thymic aplasia
• 2. Deficiency of complement factor
• 3. Inborn error of metabolism
• 4. Chromosomal anomaly

Question: A child’s CSF was examined I contains slightly raised or normal PMN cells, raised lymphocytes, absence of mycotic growth, value of protein is normal or above normal, glucose level is normal. The most probable diagnosis is____________?

• 1. Pyogenic bacterial meningitis
• 2. Viral meningitis
• 3. Fungal meningitis
• 4. Tuberculous meningitis

Question: Bone marrow stem cells differ from differ from differentiated progenitor stem cells in what respect ?

• 1. Provide differentiated terminal cells
• 2. Reconstitution of Bone marrow
• 3. Formation of the ovum
• 4. Act as a repair system for the body

Question: Which is true about Multiple myeloma ?

• 1. IgM spike increase
• 2. Direct plasma cell deposition in glomerular capilaries leads to kidney damage
• 3. IL 8 is a marker for bone lesions
• 4. Invariably increase in alkaline phosphatase