Question: Somatic mutation of PTEN is seen in________________?

• 1. Retinoblastoma
• 2. Osteosarcoma
• 3. Carcinoma breast
• 4. Endometrial Carcinoma

Question: All of the following viruses are capable of causing human cancers except________________?

• 1. papilloma virus
• 2. Hepatitis B virus
• 3. Epstein Barr virus
• 4. Parvovirus B-19

Question: Philadelphia chromosome is consistently found in_______________?

• 1. AML
• 2. CLL
• 3. CML
• 4. All of the above

Question: The cell with increased mitotic rate and resembling the undifferentiated mesenchymal cells of the same origin is______________?

• 1. Anaplastic
• 2. Dysplastic
• 3. Metaplastic
• 4. Hyperplastic

Question: A simple bacterial test for mutagenic carcinogens is________________?

• 1. Ames test
• 2. Redox text
• 3. Bacteriophage
• 4. Gene splicing

Question: The increase in the size of left kidney following the removal of right kidney (vicarious hypertrophy) is due to_______________?

• 1. Hyperplasia
• 2. Hypertrophy
• 3. Both of the above
• 4. None of the above

Question: the lesions of bone which is expansile and eccentrically ballooned out is________________?

• 1. Ossifying fibroma
• 2. Aneurysmal bone cyst
• 3. Fibrous dysplasia
• 4. None of the above

Question: Usually metastatic lesions are osteolytic, but osteoblastic secondaries occur in cancer of_______________?

• 1. Thyroid
• 2. Prostate
• 3. Kidney
• 4. Uterus

Question: Onion skin appearance is seen in_______________?

• 1. Ewing’s sarcoma
• 2. Osteosarcoma
• 3. Osteoma
• 4. Fibro sarcoma

Question: Nuclear cytoplasmic ratio in malignant cells is________________?

• 1. 1 : 6
• 2. 1 : 5
• 3. 1 : 1
• 4. 6 : 4